Pyridines and derivatives

Aromatic organic compounds consist of an aromatic six-membered ring containing one nitrogen atom and five carbon atoms; includes compounds derived from pyridines.

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6,136 – 6,150 of 178,527 results

6,136

Aobchem AOBCHEM

5001044289 2 4 6-TRIETHYLBENZALDEHYDE 1G

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6,137

Aobchem AOBCHEM

5001044656 4- 5-NITROPYRIDIN-2-YL MORPHOL

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6,138

Medchemexpress LLC Edar protein, human (HEK293, His) | >95.0% | 50 UG

Recombinant human EDAR protein expressed in HEK293 cells with a C-terminal His tag. The protein interacts with EDA-A1 and activates NF-κB and JNK signaling, making it suitable for receptor-ligand interaction studies, signaling assays, and biochemical characterization. Supplied lyophilized with reconstitution and storage guidance.

Recombinant human protein produced in HEK293 cells.
C-terminal His tag for detection and purification.
High purity: >95% as determined by reducing SDS-PAGE.
Lyophilized from PBS, pH 7.4, for enhanced stability.
Apparent molecular weight ~25-35 kDa due to glycosylation.
Suitable for receptor binding, signaling, and biochemical assays.
Store lyophilized at -20°C; after reconstitution stable short-term at 4°C; freeze aliquots for long-term storage.

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6,139

Apexbio Technology LLC Minoxidil sulphate 83701-22-8 5g

Minoxidil sulphate (CAS 83701-22-8) is a potassium channel opener specifically acting on ATP-sensitive potassium channels It is the biologically active metabolite resulting from the sulfation of minoxidil Pharmacologically minoxidil sulphate exhibits vasodilatory activity and animal studies demonstrate its capacity to stimulate hair follicle growth Consequently it serves as an important compound in biomedical research focused on conditions involving hair regrowth and restoration

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6,140

Medchemexpress LLC CCC-0975 | 432018-03-6 | 99.5% | 483.89 | 1 ML

CCC-0975 is a hepatitis B virus (HBV) inhibitor with an EC50 of 10 μM. It specifically interferes with the conversion of relaxed circular DNA (rcDNA) to covalently closed circular DNA (cccDNA), leading to a synchronous reduction of both cccDNA and its precursor, deproteinized rcDNA (DP-rcDNA). This inhibition occurs without promoting their intracellular degradation, making CCC-0975 a promising compound for chronic hepatitis B research.

functions as a hepatitis B virus (HBV) inhibitor
interferes with rcDNA to cccDNA conversion
reduces cccDNA and deproteinized rcDNA levels
does not promote intracellular degradation
shows promise for chronic hepatitis B research

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6,141

Medchemexpress LLC 2-(11-oxo-6H-benzo[c]benzoxepin-2-yl)acetic acid | 55453-87-7 | MFCD00242952 | 268.27 g/mol | C16H12O4 | 1 G

Isoxepac is an orally active non-steroidal anti-inflammatory research standard supplied as a powder for preclinical and analytical use. It is used in studies of inflammation and pain-related disease models.

cas number: 55453-87-7
chemical formula: C16H12O4
molecular weight: 268.27 g/mol
form: powder
storage: powder at -20°C for long-term, 4°C short-term; in solvent at -80°C or -20°C per guidance
solubility: soluble in DMSO (100 mg/mL); formulations available for in vivo dosing
applications: inflammatory and pain-related preclinical research and analytical assays

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6,142

Medchemexpress LLC Trans-(1R,2R)-N-[(2S)-1-[4-(5-bromo-2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propan-2-yl]-2-phenyl | 1246303-14-9 | 98.1% | 497.43 g·mol⁻¹ | C25H29BrN4O2 | 1 ML

VU0359595 is a selective pharmacological inhibitor of phospholipase D1 (PLD1) supplied as a ready-to-use solution for research applications. It is offered as a 10 mM solution in DMSO and as a solid, providing flexibility for assay setup and compound handling. The material is reported at high purity and is intended for biochemical and cellular studies of PLD1-dependent signaling pathways.

Selective phospholipase D1 inhibitor
Ready-to-use 10 mM solution in DMSO
High purity, 98.06%
Suitable for biochemical and cellular assays
Also available as solid in multiple packaging sizes

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6,143

Apexbio Technology LLC Cidofovir dihydrate 149394-66-1 10mM (in 1mL H2O)

Cidofovir dihydrate (CAS 149394-66-1) is a small-molecule inhibitor targeting viral DNA polymerase It is designed to selectively inhibit viral DNA synthesis thereby blocking viral DNA chain elongation and replication Cidofovir dihydrate exerts its biological activity primarily through intracellular conversion to its active diphosphate form which competitively inhibits viral DNA polymerase In cell-based studies cidofovir dihydrate demonstrates inhibitory potency against cytomegalovirus (CMV) replication typically achieving IC50 values in the low micromolar range in CMV-infected cell culture models Based on these pharmacological properties cidofovir dihydrate holds research potential in studies of antiviral efficacy virus-host interactions and antiviral resistance mechanisms

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6,144

Apexbio Technology LLC WP1066 857064-38-1 25mg

WP1066 (CAS 857064-38-1) is a small molecule analog of AG490 and functions primarily as an inhibitor of Janus kinase 2 (JAK2) It disrupts JAK2 signaling by reducing phosphorylation and promoting degradation of the JAK2 protein thereby inhibiting downstream STAT3/STAT5 transcription factors and the phosphoinositide-3 kinase pathway WP1066 has demonstrated antiproliferative and pro-apoptotic activity in models of acute myeloid leukemia (AML) including patient-derived AML cells and AML cell lines (OCIM2 K562) Additionally WP1066 shows inhibitory effects against tumor growth and angiogenesis in renal cell carcinoma (RCC) model systems highlighting its potential for hematologic cancers and RCC therapeutic research

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6,145

Medchemexpress LLC CD97 protein, human (HEK293, hFc) | >90.0% | 50 UG

Recombinant human CD97 Fc-tagged protein (residues Q21-Q398 fused to C-terminal human Fc) expressed in HEK293 mammalian cells. Supplied as a sterile, 0.22 μm-filtered PBS solution (pH 7.4), the glycosylated protein is intended for biochemical and binding assays and demonstrates binding to human CD55 in ELISA.

Recombinant fragment Q21-Q398 fused to human Fc.
Expressed in HEK293 cells with mammalian glycosylation.
Purity greater than 90% by reducing SDS-PAGE.
Endotoxin level below 1 EU/μg (LAL method).
Molecular weight approximately 100-110 kDa.
Supplied as a 0.22 μm filtered PBS solution, pH 7.4.
Measured binding to CD55 with ELISA (linear range 1.28-32 ng/mL).
Shipped on dry ice; store at -80°C and avoid repeated freeze-thaw cycles.

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6,146

Medchemexpress LLC LolCDE-IN-2 | 2748443-01-6 | 99.6% | 1 ML

LolCDE-IN-2 is a potent inhibitor of the Lol protein (LolCDE), demonstrating antibacterial activity. It effectively inhibits E. coli MG1655 and increases the susceptibility of P. aeruginosa ΔlolCDE::CTX-lolCDE E. coli strain under specific conditions.

Potent Lol protein (LolCDE) inhibitor.
Exhibits antibacterial activity.
Inhibits E. coli MG1655 with an MIC of 2 μg/ml.
Increases susceptibility of P. aeruginosa ΔlolCDE::CTX-lolCDE E. coli strain under specific conditions.

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6,147

FUJIFILM BIOSCIENCES INC NDSB-256

This product is a non-surfactant with zwitterionic character It is used for the extraction of membrane proteins and nuclear proteins the refolding of denatured proteins and the crystallization of proteins NDSB-256 is zwitterionic compound which have a quaternary ammonium ion acidic and hydrophilic sulfonate and short hydrophobic group in one molecule Such compound that has hydrophilic and hydrophobic groups in the molecule typically form micelle and is called as surfactant but NDSB-256 does not form micelle due to those short hydrophobic groups Readily removed by dialysis as micelle is not formed Keep zwitterionic character in a wide range of pH For research use only RUO

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6,148

Medchemexpress LLC Transferrin Mouse 100ug

Transferrin is an important iron-binding transport protein that combines two Fe(3 ) ions with an anion usually bicarbonate Its main function is to transport iron from the site of absorption to the site of storage and utilization Transferrin Protein Mouse (HEK293 Fc) is the recombinant mouse-derived Transferrin protein expressed by HEK293 with C-hFc labeled tag

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6,149

Medchemexpress LLC 2,4-Imidazolidinedione, 5-hydroxy-1-methyl- | 84210-26-4 | 98.0% | 130.10 | 10 MG

NZ 419 (5-Hydroxy-1-methylhydantoin) is a metabolite of creatinine and an antioxidant with oral activity, which has the ability to scavenge hydroxyl radicals (•OH). It can inhibit the progression of chronic kidney disease (CKD) in rats.

Metabolite of creatinine
Antioxidant with oral activity
Scavenges hydroxyl radicals (•OH)
Inhibits progression of chronic kidney disease in rats

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6,150

Medchemexpress LLC 20-hede | 240427-90-1 | 97.1% | 324.50 | C20H36O3 | 1 MG

20-HEDE (WIT 002) is a small-molecule antagonist of 20-hydroxyeicosatetraenoic acid (20-HETE) provided as a high-purity research chemical for laboratory studies of cytochrome P450 metabolites and eicosanoid signaling. It is intended for research use only and includes documented solubility and storage recommendations to support experimental handling.

High purity suitable for research applications.
Molecular weight 324.50; molecular formula C20H36O3.
Soluble in DMSO at 100 mg/mL; ultrasonic assistance recommended.
Storage: pure form -20°C up to 3 years; in solvent -80°C 6 months or -20°C 1 month.
Available in small-quantity packaging for experimental use.

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Pyridines and derivatives

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Medchemexpress LLC Edar protein, human (HEK293, His) | >95.0% | 50 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Minoxidil sulphate 83701-22-8 5g Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CCC-0975 | 432018-03-6 | 99.5% | 483.89 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2-(11-oxo-6H-benzo[c]benzoxepin-2-yl)acetic acid | 55453-87-7 | MFCD00242952 | 268.27 g/mol | C16H12O4 | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Cidofovir dihydrate 149394-66-1 10mM (in 1mL H2O) Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC WP1066 857064-38-1 25mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC CD97 protein, human (HEK293, hFc) | >90.0% | 50 UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LolCDE-IN-2 | 2748443-01-6 | 99.6% | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Transferrin Mouse 100ug Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 2,4-Imidazolidinedione, 5-hydroxy-1-methyl- | 84210-26-4 | 98.0% | 130.10 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 20-hede | 240427-90-1 | 97.1% | 324.50 | C20H36O3 | 1 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More